Abnormalities of cAMP signaling in affective disorders: implication for pathophysiology and treatment.

@article{Prez2000AbnormalitiesOC,
  title={Abnormalities of cAMP signaling in affective disorders: implication for pathophysiology and treatment.},
  author={J. Zu{\~n}iga P{\'e}rez and Daniela Tardito and Silvia Satiko Onoyama Mori and Giorgio Racagni and Enrico Smeraldi and Raffaella Zanardi},
  journal={Bipolar disorders},
  year={2000},
  volume={2 1},
  pages={
          27-36
        }
}
OBJECTIVE During the last decade, much attention has been given to the role of signal transduction pathways in affective disorders. This review describes the possible role of the cAMP signaling in such disorders. METHODS Among the components of cAMP signaling, this review focuses on the cAMP-dependent phosphorylation system. We analyzed the basic components of the cAMP-dependent phosphorylation system and the preclinical evidence supporting their involvement in the biochemical action of… CONTINUE READING

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