Abnormalities in hemostasis in acute promyelocytic leukemia.

@article{Kwaan2002AbnormalitiesIH,
  title={Abnormalities in hemostasis in acute promyelocytic leukemia.},
  author={Hau C. Kwaan and Jun Wang and Lisa N. Boggio},
  journal={Hematological oncology},
  year={2002},
  volume={20 1},
  pages={33-41}
}
Our understanding of the hemostatic abnormalities in acute promyelocytic leukemia (APL) has undergone remarkable changes over the past three decades. Hemorrhagic complications lead to significant morbidity and mortality in patients with APL. Up to 30% of early deaths are due to hemorrhagic complications. Our concept of the coagulation changes in APL have evolved from a simple belief that the bleeding was due to disseminated intravascular coagulation (DIC) from underlying infection, to a… CONTINUE READING

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