Abnormalities in Schwann cell sheaths in spinal nerve roots of dystrophic mice.

Abstract

Dorsal and ventral spinal roots at cervical, thoracic, lumbar and sacral levels in dystrophic, dy/dy, mice of both 129/ReJ and C57Bl/6J phenotypes showed a complete lack of Schwann cell sheaths of any sort around the majority of their nerve fibres. This condition, termed amyelination, is more extensive (up to 1-5 cm in length) in the longer lumbar and… (More)

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