Abnormalities in P300 components in depression: an ERP-sLORETA study

@article{Zhou2019AbnormalitiesIP,
  title={Abnormalities in P300 components in depression: an ERP-sLORETA study},
  author={Lina Zhou and Gaohua Wang and Cai-ling Nan and Hui-ling Wang and Zhongchun Liu and Hanping Bai},
  journal={Nordic Journal of Psychiatry},
  year={2019},
  volume={73},
  pages={1 - 8}
}
Abstract Background: Alterations in P300 components occur in depressed patients, but the brain regions contributing to these changes remain unclear. Aims: Thus, the aim of the present study was to examine the underlying neural activation of P300 components in patients with depression to explore brain regions related to depression. Methods: P300 components were evoked by an oddball auditory paradigm and recorded from 30 patients with current depression, as well as 30 age-, gender-, and education… 
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References

SHOWING 1-10 OF 53 REFERENCES
Abnormalities of P300 cortical current density in unmedicated depressed patients revealed by LORETA analysis of event‐related potentials
TLDR
The results revealed that N100 cortical current density did not differ between the two groups, while P300 cortical current densities were significantly lower in depressed patients over the bilateral temporal lobes, the left frontal region, and the right temporal–parietal area, thus supporting the hypothesis of right hemisphere dysfunction in depression.
Source Activation of P300 Correlates with Negative Symptom Severity in Patients with Schizophrenia
TLDR
The found that the P300 amplitude of schizophrenia patients was significantly decreased along the midline electrodes and both bilateral temporal areas compared with healthy controls, and the reduced P300 source activation in schizophrenia might reflect deficits in fronto-temporal-parietal circuit.
A study of P300-event related evoked potential in the patients of major depression.
TLDR
The results suggest that P300 latency is longer in the patients of major depression disorders which could be due to constitutive altered 'cognitive neuronal pool' or a neurotransmitter/neuropeptide imbalance.
Structural and energetic processes related to P300: LORETA findings in depression and effects of antidepressant drugs.
TLDR
ERP-tomography identified changes in energetic sources in brain areas predominantly involved in depression and in antidepressant action in menopausal depressed patients and elderly healthy subjects.
Alterations of P300 wave in occipital lobe in depressive patients.
TLDR
Neurofunctional alterations in the occipital lobe during visual discrimination and memory task in patients with depression are revealed, revealing negative correlation between the P300 amplitude and severity of the depression.
Auditory P3a and P3b neural generators in schizophrenia: An adaptive sLORETA P300 localization approach
P300 in major depressive disorder
Impact of depression heterogeneity on attention: an auditory oddball event related potential study.
Auditory event-related potentials in 50 melancholic patients: increased N100, N200 and P300 latencies and diminished P300 amplitude.
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