Abnormalities in A-to-I RNA editing patterns in CNS injuries correlate with dynamic changes in cell type composition

@inproceedings{GalMark2017AbnormalitiesIA,
  title={Abnormalities in A-to-I RNA editing patterns in CNS injuries correlate with dynamic changes in cell type composition},
  author={Nurit Gal-Mark and Lea Shallev and Sahar Sweetat and Michal Barak and Jin Billy Li and Erez Y. Levanon and Eli Eisenberg and Oded Behar},
  booktitle={Scientific reports},
  year={2017}
}
Adenosine to Inosine (A-to-I) RNA editing is a co- or post-transcriptional mechanism that modifies genomically encoded nucleotides at the RNA level. A-to-I RNA editing is abundant in the brain, and altered editing levels have been reported in various neurological pathologies and following spinal cord injury (SCI). The prevailing concept is that the RNA editing process itself is dysregulated by brain pathologies. Here we analyzed recent RNA-seq data, and found that, except for few mammalian… CONTINUE READING
4 Citations
57 References
Similar Papers

References

Publications referenced by this paper.
Showing 1-10 of 57 references

The Search for True Numbers of Neurons and Glial Cells in the Human Brain: A Review of 150 Years of Cell Counting

  • C. S. von Bartheld, J. Bahney, S. Herculano-Houzel
  • J. Comp. Neurol. doi: 10.1002/cne.24040
  • 2016

editing in Alzheimer ’ s disease

  • S. Maas, Y. Kawahara, K. M. Tamburro, K. Nishikura
  • 2016

A survey of human brain transcriptome diversity at the single cell level

  • S Darmanis
  • Proc. Natl. Acad. Sci. USA
  • 2015

Similar Papers

Loading similar papers…