Abnormal white matter connections between medial frontal regions predict symptoms in patients with first episode schizophrenia.

@article{Ohtani2015AbnormalWM,
  title={Abnormal white matter connections between medial frontal regions predict symptoms in patients with first episode schizophrenia.},
  author={Toshiyuki Ohtani and Sylvain Bouix and Amanda E. Lyall and Taiga Hosokawa and Yukiko Saito and Eric D Melonakos and Carl-Fredrik Westin and Larry J. Seidman and Jill M. Goldstein and Raquelle I. Mesholam-Gately and Tracey L. Petryshen and Joanne D Wojcik and Marek Kubicki},
  journal={Cortex; a journal devoted to the study of the nervous system and behavior},
  year={2015},
  volume={71},
  pages={264-76}
}
INTRODUCTION The medial orbitofrontal cortex (mOFC) and rostral part of anterior cingulate cortex (rACC) have been suggested to be involved in the neural network of salience and emotional processing, and associated with specific clinical symptoms in schizophrenia. Considering the schizophrenia dysconnectivity hypothesis, the connectivity abnormalities between mOFC and rACC might be associated with clinical characteristics in first episode schizophrenia patients (FESZ). METHODS After… CONTINUE READING
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