Abnormal ventilatory response to exercise in adults with congenital heart disease relates to cyanosis and predicts survival.

@article{Dimopoulos2006AbnormalVR,
  title={Abnormal ventilatory response to exercise in adults with congenital heart disease relates to cyanosis and predicts survival.},
  author={Konstantinos Dimopoulos and Darlington O. Okonko and Gerhard-Paul Diller and Craig S. Broberg and Tushar Vilas Salukhe and Sonya Babu-Narayan and Wei Li and Anselm S Uebing and Stephanie Bayne and Roland Wensel and Massimo Francesco Piepoli and P Poole-wilson and Darrel P. Francis and Michael A. Gatzoulis},
  journal={Circulation},
  year={2006},
  volume={113 24},
  pages={2796-802}
}
BACKGROUND Limited data exist with which to stratify risk in adult congenital heart disease (ACHD). An increased ventilatory response to exercise, expressed as ventilation per unit of carbon dioxide production (V(E)/V(CO2) slope), is an established predictor of impaired survival in acquired heart disease. We sought to establish the distribution, relation to cyanosis, and prognostic value of the V(E)/V(CO2) slope across a wide spectrum of ACHD patients. METHODS AND RESULTS Five hundred sixty… CONTINUE READING

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