Abnormal subcortical deep-gray matter susceptibility-weighted imaging filtered phase measurements in patients with multiple sclerosis: A case-control study

@article{Zivadinov2012AbnormalSD,
  title={Abnormal subcortical deep-gray matter susceptibility-weighted imaging filtered phase measurements in patients with multiple sclerosis: A case-control study},
  author={Robert Zivadinov and Mari Heininen-Brown and Claudiu V. Schirda and Guy U. Poloni and Niels P Bergsland and Christopher R. Magnano and Jacqueline Durfee and Cheryl Kennedy and Ellen Carl and Jesper Hagemeier and Ralph H. B. Benedict and Bianca Weinstock-Guttman and Michael G. Dwyer},
  journal={NeuroImage},
  year={2012},
  volume={59},
  pages={331-339}
}
OBJECTIVE To investigate abnormal phase on susceptibility-weighted imaging (SWI)-filtered phase images indicative of iron content, in subcortical deep-gray matter (SDGM) of multiple sclerosis (MS) patients and healthy controls (HC), and to explore its relationship with MRI outcomes. METHODS 169 relapsing-remitting (RR) and 64 secondary-progressive (SP) MS patients, and 126 age- and sex-matched HC were imaged on a 3T scanner. Mean phase of the abnormal phase tissue (MP-APT), normal phase… CONTINUE READING

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