Abnormal small-world architecture of top-down control networks in obsessive-compulsive disorder.

  title={Abnormal small-world architecture of top-down control networks in obsessive-compulsive disorder.},
  author={Tijiang Zhang and Jinhui Wang and Yanchun Yang and Qizhu Wu and Bin Li and Long Chen and Qiang Yue and Hehan Tang and Chaogan Yan and Su Lui and Xiaoqi Huang and Raymond C K Chan and Yufeng Zang and Yong He and Qiyong Gong},
  journal={Journal of psychiatry & neuroscience : JPN},
  volume={36 1},
BACKGROUND Obsessive-compulsive disorder (OCD) is a common neuropsychiatric disorder that is characterized by recurrent intrusive thoughts, ideas or images and repetitive ritualistic behaviours. Although focal structural and functional abnormalities in specific brain regions have been widely studied in populations with OCD, changes in the functional relations among them remain poorly understood. This study examined OCD-related alterations in functional connectivity patterns in the brain's top… CONTINUE READING


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