Abnormal skeletal patterning in embryos lacking a single Cbp allele: a partial similarity with Rubinstein-Taybi syndrome.

@article{Tanaka1997AbnormalSP,
  title={Abnormal skeletal patterning in embryos lacking a single Cbp allele: a partial similarity with Rubinstein-Taybi syndrome.},
  author={Yasunori Tanaka and Ichiro Naruse and Takaki Maekawa and Hiroshi Masuya and Toshihiko Shiroishi and Seiji Ishii},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1997},
  volume={94 19},
  pages={10215-20}
}
CBP is a transcriptional coactivator required by many transcription factors for transactivation. Rubinstein-Taybi syndrome, which is an autosomal dominant syndrome characterized by abnormal pattern formation, has been shown to be associated with mutations in the Cbp gene. Furthermore, Drosophila CBP is required in hedgehog signaling for the expression of decapentapleigic, the Drosophila homologue of bone morphogenetic protein. However, no direct evidence exists to indicate that loss of one copy… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 106 extracted citations

References

Publications referenced by this paper.
Showing 1-3 of 3 references

Development (Cambridge, U.K

  • R. Mo, A. M. Freer, +13 authors C.-C
  • 1997

Tanaka et al

  • V. E. Ghouzzi, M. L. Merrer, +10 authors 42–46. 10220 Developmental Biology
  • Proc. Natl. Acad. Sci. USA 94
  • 1997
1 Excerpt

Congenital Anomalies 16, 171–173

  • M. Inouye
  • 1976
2 Excerpts

Similar Papers

Loading similar papers…