Abnormal sex-duct development in female moles: the role of anti-Müllerian hormone and testosterone.

@article{Zurita2003AbnormalSD,
  title={Abnormal sex-duct development in female moles: the role of anti-M{\"u}llerian hormone and testosterone.},
  author={Federico Zurita and Francisco J Barrionuevo and Philippe Berta and Esperanza Ortega and Miguel Burgos and Rafael Jim{\'e}nez},
  journal={The International journal of developmental biology},
  year={2003},
  volume={47 6},
  pages={451-8}
}
We have performed a morphological, hormonal and molecular study of the development of the sex ducts in the mole Talpa occidentalis. Females develop bilateral ovotestes with a functional ovarian portion and disgenic testicular tissue. The Müllerian ducts develop normally in females and their regression is very fast in males, suggesting a powerful action of the anti-Müllerian hormone in the mole. RT-PCR demonstrated that the gene governing this hormone begins to be expressed in males coinciding… CONTINUE READING

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