Abnormal quantity and function of regulatory T cells in peripheral blood of patients with severe aplastic anemia.

Abstract

Severe aplastic anemia is a rare autoimmune disease characterized by severe pancytopenia and bone marrow failure, which is caused by activated T lymphocytes. Tregs are believed to control development and progression of autoimmunity by suppressing autoreactive T cells. This study aims at understanding the quantity and function of peripheral Tregs in SAA. The… (More)
DOI: 10.1016/j.cellimm.2015.04.001

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