Abnormal pupillary light reflex with chromatic pupillometry in Gaucher disease

@article{Narita2014AbnormalPL,
  title={Abnormal pupillary light reflex with chromatic pupillometry in Gaucher disease},
  author={Aya Narita and Kentaro Shirai and Norika Kubota and Rumiko Takayama and Yukitoshi Takahashi and Takanori Onuki and Chikahiko Numakura and Mitsuhiro Kato and Yusuke Hamada and Norio Sakai and Atsuko Ohno and Maya Asami and Shoko Matsushita and Anri Hayashi and Tomohiro Kumada and Tatsuya Fujii and Asako Horino and Takeshi Inoue and Ichiro Kuki and Ken Asakawa and Hitoshi Ishikawa and Koyo Ohno and Yoko Nishimura and Akiko Tamasaki and Yoshihiro Maegaki and Kousaku Ohno},
  journal={Annals of Clinical and Translational Neurology},
  year={2014},
  volume={1},
  pages={135 - 140}
}
The hallmark of neuronopathic Gaucher disease (GD) is oculomotor abnormalities, but ophthalmological assessment is difficult in uncooperative patients. Chromatic pupillometry is a quantitative method to assess the pupillary light reflex (PLR) with minimal patient cooperation. Thus, we investigated whether chromatic pupillometry could be useful for neurological evaluations in GD. In our neuronopathic GD patients, red light‐induced PLR was markedly impaired, whereas blue light‐induced PLR was… Expand
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