Abnormal pattern of platelet APP isoforms in Alzheimer disease and Down syndrome.

@article{Luca1996AbnormalPO,
  title={Abnormal pattern of platelet APP isoforms in Alzheimer disease and Down syndrome.},
  author={Monica di Luca and Lucia Pastorino and Flaminio Cattabeni and Raffaella Zanardi and Silvio Scarone and Giorgio Racagni and Enrico Smeraldi and Julio P{\'e}rez},
  journal={Archives of neurology},
  year={1996},
  volume={53 11},
  pages={1162-6}
}
OBJECTIVE To determine if changes in levels of amyloid precursor protein (APP) isoforms in periphery are associated with Alzheimer disease and Down syndrome. DESIGN After subjects were grouped according to diagnosis, APP isoform levels in platelets were compared. SETTING University medical center. SUBJECTS Ten patients who fulfilled diagnostic criteria for probable Alzheimer disease, 22 healthy volunteers, and 7 elderly (mean age, 42.7 years) and 7 young (mean age, 19.0 years) patients… CONTINUE READING
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