Abnormal neuropeptide concentration in rectal mucosa of patients with inflammatory bowel disease

@article{Yamamoto1996AbnormalNC,
  title={Abnormal neuropeptide concentration in rectal mucosa of patients with inflammatory bowel disease},
  author={Hitoshi Yamamoto and Kimitomo Morise and Kazuo Kusugami and Atsushi Furusawa and T. Konagaya and Yuji Nishio and Hiroshi Kaneko and Kiyoshi Uchida and Hirofumi Nagai and Terunori Mitsuma and Hiroshi Nagura},
  journal={Journal of Gastroenterology},
  year={1996},
  volume={31},
  pages={525-532}
}
Regulatory neuropeptides are widely distributed in the gastrointestinal tract, where they play an important role in motility, secretion, and immune and inflammatory responses. In this study, the rectal mucosal content of somatostatin (SOM), substance P (SP), β-endorphin (BE), and thyrotropin-releasing hormone (TRH) was measured by radioimmunoassay in 56 patients with ulcerative colitis (UC), 15 patients with Crohn's disease (CD), 15 patients with acute infectious colitis (AIC), and 11 controls… CONTINUE READING

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