Abnormal neural oscillations and synchrony in schizophrenia
@article{Uhlhaas2010AbnormalNO,
title={Abnormal neural oscillations and synchrony in schizophrenia},
author={P. J. Uhlhaas and Wolf J. Singer},
journal={Nature Reviews Neuroscience},
year={2010},
volume={11},
pages={100-113}
}Converging evidence from electrophysiological, physiological and anatomical studies suggests that abnormalities in the synchronized oscillatory activity of neurons may have a central role in the pathophysiology of schizophrenia. Neural oscillations are a fundamental mechanism for the establishment of precise temporal relationships between neuronal responses that are in turn relevant for memory, perception and consciousness. In patients with schizophrenia, the synchronization of beta- and gamma… CONTINUE READING
Figures, Tables, and Topics from this paper
Paper Mentions
Interventional Clinical Trial
Transcranial alternating current stimulation (tACS) and transcranial random noise stimulation
(tRNS) are two (CE marked medical devices) new, non-invasive (over the scalp) brain… Expand
| Conditions | Dysphagia, Swallowing Disorder |
|---|---|
| Intervention | Device |
Interventional Clinical Trial
This study proposes to assess the effect of trans-cranial direct current stimulation (tDCS)
on cognitive control, working memory, functional, clinical, and cognitive outcomes in… Expand
| Conditions | Psychosis, Schizophrenia |
|---|---|
| Intervention | Device |
1,480 Citations
Brain functional connectivity and the pathophysiology of schizophrenia.
- Psychology, Medicine
- Psychiatrike = Psychiatriki
- 2014
- 4
High-frequency oscillations and the neurobiology of schizophrenia
- Psychology, Medicine
- Dialogues in clinical neuroscience
- 2013
- 132
- PDF
Oscillations and Neuronal Dynamics in Schizophrenia: The Search for Basic Symptoms and Translational Opportunities
- Psychology, Medicine
- Biological Psychiatry
- 2015
- 155
- PDF
Neural synchrony and the development of cortical networks
- Psychology, Medicine
- Trends in Cognitive Sciences
- 2010
- 367
Alterations of Cortical GABA Neurons and Network Oscillations in Schizophrenia
- Psychology, Medicine
- Current psychiatry reports
- 2010
- 230
Impaired GABAergic Neurotransmission in Schizophrenia Underlies Impairments in Cortical Gamma Band Oscillations
- Psychology, Medicine
- Current Psychiatry Reports
- 2013
- 37
Neural oscillations as a translational tool in schizophrenia research: Rationale, paradigms and challenges
- Psychology, Medicine
- Journal of psychopharmacology
- 2015
- 19
References
SHOWING 1-10 OF 212 REFERENCES
Neural Synchrony in Brain Disorders: Relevance for Cognitive Dysfunctions and Pathophysiology
- Psychology, Medicine
- Neuron
- 2006
- 1,591
- PDF
Neural synchrony indexes disordered perception and cognition in schizophrenia.
- Psychology, Medicine
- Proceedings of the National Academy of Sciences of the United States of America
- 2004
- 543
- PDF
Dysfunctional Long-Range Coordination of Neural Activity during Gestalt Perception in Schizophrenia
- Psychology, Medicine
- The Journal of Neuroscience
- 2006
- 408
- PDF
Schizophrenia and the disconnection hypothesis
- Medicine, Psychology
- Acta psychiatrica Scandinavica. Supplementum
- 1999
- 285
Gamma Band Oscillations Reveal Neural Network Cortical Coherence Dysfunction in Schizophrenia Patients
- Psychology, Medicine
- Biological Psychiatry
- 2006
- 350
Cortical Oscillatory Activity Is Critical for Working Memory as Revealed by Deficits in Early-Onset Schizophrenia
- Psychology, Medicine
- The Journal of Neuroscience
- 2009
- 261
- PDF
Cortical inhibitory neurons and schizophrenia
- Biology, Medicine
- Nature Reviews Neuroscience
- 2005
- 1,982
- PDF
Cortical gamma generators suggest abnormal auditory circuitry in early-onset psychosis.
- Psychology, Medicine
- Cerebral cortex
- 2008
- 82
- PDF
The reduced neuropil hypothesis: a circuit based model of schizophrenia
- Psychology, Medicine
- Biological Psychiatry
- 1999
- 857