Abnormal neural oscillations and synchrony in schizophrenia

@article{Uhlhaas2010AbnormalNO,
  title={Abnormal neural oscillations and synchrony in schizophrenia},
  author={P. J. Uhlhaas and Wolf J. Singer},
  journal={Nature Reviews Neuroscience},
  year={2010},
  volume={11},
  pages={100-113}
}
  • P. J. Uhlhaas, Wolf J. Singer
  • Published 2010
  • Psychology, Medicine
  • Nature Reviews Neuroscience
  • Converging evidence from electrophysiological, physiological and anatomical studies suggests that abnormalities in the synchronized oscillatory activity of neurons may have a central role in the pathophysiology of schizophrenia. Neural oscillations are a fundamental mechanism for the establishment of precise temporal relationships between neuronal responses that are in turn relevant for memory, perception and consciousness. In patients with schizophrenia, the synchronization of beta- and gamma… CONTINUE READING
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    References

    SHOWING 1-10 OF 212 REFERENCES
    Abnormal Neural Synchrony in Schizophrenia
    • 564
    • PDF
    Neural synchrony indexes disordered perception and cognition in schizophrenia.
    • 543
    • PDF
    Dysfunctional Long-Range Coordination of Neural Activity during Gestalt Perception in Schizophrenia
    • 408
    • PDF
    Schizophrenia and the disconnection hypothesis
    • Karl J. Friston
    • Medicine, Psychology
    • Acta psychiatrica Scandinavica. Supplementum
    • 1999
    • 285
    Cortical inhibitory neurons and schizophrenia
    • 1,982
    • PDF
    The reduced neuropil hypothesis: a circuit based model of schizophrenia
    • 857