Abnormal heart rate variability and/or late potentials in hypertensive left ventricular hypertrophy: are they chickens, eggs or an omelette?


Surrogate markers are common in cardiology and represent a measurement which has a direct or indirect relationship to patient outcomes. Their individual clinical usefulness depends on statistical sensitivity, specificity, reproducibility and importantly a demonstrable pathophysiological relationship to cardiac events. Surrogate measurements are increasingly… (More)
DOI: 10.1038/sj.jhh.1000560


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