Abnormal glycosylation of serum IgG in patients with IgA nephropathy

  title={Abnormal glycosylation of serum IgG in patients with IgA nephropathy},
  author={Hideki Homma and Keiichi Tozawa and Takahiro Yasui and Yasunori Itoh and Yutaro Hayashi and Kenjiro Kohri},
  journal={Clinical and Experimental Nephrology},
We postulated that IgA nephropathy (IgAN) involved alterations of serum IgG. The present study was undertaken to elucidate changes in serum IgG oligosaccharide structure analysis and to assess the diagnostic usefulness of this analysis in IgAN. The subjects were 28 children who were definitively diagnosed as having IgAN on the basis of renal biopsy and who had not received treatment for this disease; 27 healthy children; 15 untreated adults definitely diagnosed as having IgAN; 5 patients with… CONTINUE READING

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