Abnormal forebrain activity in functional bowel disorder patients with chronic pain.

  title={Abnormal forebrain activity in functional bowel disorder patients with chronic pain.},
  author={Chun L. Kwan and Nicholas E. Diamant and Geoff Pope and Kristi Mikula and David J. Mikulis and Karen D. Davis},
  volume={65 8},
BACKGROUND Abnormal cortical pain responses in patients with fibromyalgia and conversion disorder raise the possibility of a neurobiologic basis underlying so-called "functional" chronic pain. OBJECTIVE To use percept-related fMRI to test the hypothesis that patients with a painful functional bowel disorder do not process visceral input or sensations normally or effectively at the cortical level. METHODS Eleven healthy subjects and nine patients with irritable bowel syndrome (IBS) underwent… CONTINUE READING
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TPJ, temporoparietal junction; sma, supplementary motor area; M1, primary motor cortex. Note that Talairach coordinates of brain activations are indicated in parentheses

  • TPJ, temporoparietal junction; sma, supplementary…

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