Abnormal expression of chemokine receptors in Behçet's disease: relationship to intracellular Th1/Th2 cytokines and to clinical manifestations.

@article{Houman2004AbnormalEO,
  title={Abnormal expression of chemokine receptors in Behçet's disease: relationship to intracellular Th1/Th2 cytokines and to clinical manifestations.},
  author={Habib Houman and Agn{\'e}s Hamzaoui and Imed Ben Ghorbal and Monia Smiti Khanfir and Moncef Feki and Kamel Hamzaoui},
  journal={Journal of autoimmunity},
  year={2004},
  volume={23 3},
  pages={267-73}
}
Dynamic interplay between cytokines and chemokines directs trafficking of peripheral blood mononuclear cells to tissues in autoimmune and/or viral diseases. The aim of the current study was to define the expression on CD3+ T cells of six chemokine receptors associated with inflammatory sites and the expression of intracellular cytokines, such as interferon-gamma (IFN-gamma) and interleukin-4 (IL-4), in Behcet's disease (BD). Flow cytometry was used to detect chemokine receptor and… CONTINUE READING