Abnormal expression of TIMP-2, SOD, vimentin and PAI proteins in cloned bovine placentae.

  title={Abnormal expression of TIMP-2, SOD, vimentin and PAI proteins in cloned bovine placentae.},
  author={H-R Kim and K. Naruse and H.-R. Lee and R. Han and C-S Park and D. Jin},
  journal={Reproduction in domestic animals = Zuchthygiene},
  volume={44 4},
  • H-R Kim, K. Naruse, +3 authors D. Jin
  • Published 2009
  • Biology, Medicine
  • Reproduction in domestic animals = Zuchthygiene
Cloned mammals suffer from high rates of placental abnormality and foetal loss during pregnancy. We previously used 2-D gel electrophoresis and mass spectrometry for global proteomic analysis of cloned and normal bovine placentae to identify differential protein expression patterns. Here, we used Western blot analysis to confirm the expression levels of several pregnancy-related proteins putatively identified as being differentially expressed in somatic cell nuclear transfer (SCNT) vs normal… Expand
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