Abnormal expression of M1/MUC5AC mucin in distal colon of patients with diverticulitis, ulcerative colitis and cancer.

@article{ForgueLafitte2007AbnormalEO,
  title={Abnormal expression of M1/MUC5AC mucin in distal colon of patients with diverticulitis, ulcerative colitis and cancer.},
  author={Marie-Elisabeth Forgue-Lafitte and Bettina Fabiani and Pierre P. L{\'e}vy and Nicole Maurin and Jean-François Fl{\'e}jou and J. A. Jr. Bara},
  journal={International journal of cancer},
  year={2007},
  volume={121 7},
  pages={
          1543-9
        }
}
The abnormal expression of gastric M1/MUC5AC mucin in precancerous lesions and colon cancer evidenced by immunohistochemistry led us to check for its presence in the mucus obtained directly from patients undergoing surgery for cancerous (adenocarcinoma) or inflammatory (diverticulitis or ulcerative colitis) diseases. In parallel, the authors quantified aberrant crypt foci (ACF) and their immunolabelling by M1/MUC5AC in mucosae of cancer and diverticulitis patients. Immuno-Radio-Metric Assay of… CONTINUE READING
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