Abnormal erythrocyte and lymphocyte chemiluminescence in chronic granulomatous disease: evidence for a generalized membrane defect.

Abstract

Concanavalin A (soluble)- and/or opsonized zymosan (particulate)-stimulated luminol-dependent chemiluminescence was demonstrated in normal human lymphocytes, erythrocytes, and in the membrane (ghost) fractions of polymorphonuclear neutrophils and erythrocytes. By contrast, seven patients with chronic granulomatous disease (five boys with the X-linked type… (More)

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