Abnormal embryonic karyotype is the most frequent cause of recurrent miscarriage.

@article{SugiuraOgasawara2012AbnormalEK,
  title={Abnormal embryonic karyotype is the most frequent cause of recurrent miscarriage.},
  author={M. Sugiura-Ogasawara and Y. Ozaki and K. Katano and N. Suzumori and T. Kitaori and E. Mizutani},
  journal={Human reproduction},
  year={2012},
  volume={27 8},
  pages={
          2297-303
        }
}
BACKGROUND We previously found that a normal karyotype in a previous miscarriage is a predictor of subsequent miscarriage. However, the prevalence of recurrent miscarriage caused by an abnormal embryonic karyotype has not yet been reported, since embryonic karyotype is not typically analyzed during conventional examinations. METHODS A total of 482 patients who underwent both embryonic karyotype determination and conventional examinations for recurrent miscarriage were enrolled in this study… Expand
Chromosomal karyotype in chorionic villi of recurrent spontaneous abortion patients.
Genetic findings in miscarriages and their relation to the number of previous miscarriages
Maternal age, history of miscarriage, and embryonic/fetal size are associated with cytogenetic results of spontaneous early miscarriages
Karyotype evaluation of repeated abortions in primary and secondary recurrent pregnancy loss
Management of recurrent miscarriage
Detection of chromosomal abnormalities in spontaneous miscarriage by low-coverage next-generation sequencing
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