Abnormal dietary regulation of erythrocyte insulin receptor affinity in non-insulin-dependent diabetes mellitus.

Abstract

Decreased insulin binding to receptors is associated with the insulin resistance of obese and non-obese non-insulin-dependent diabetics. 'Down Regulation' by elevated insulin levels has been suggested as the cause, but factors influencing receptor affinity have not been examined. To investigate the control of receptors in diabetes, 10 non-insulin-dependent… (More)

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