Abnormal cerebral metabolite concentrations in patients with probable Alzheimer disease.

@article{Moats1994AbnormalCM,
  title={Abnormal cerebral metabolite concentrations in patients with probable Alzheimer disease.},
  author={Rex A. Moats and Thomas Ernst and T K Shonk and Brian D. Ross},
  journal={Magnetic resonance in medicine},
  year={1994},
  volume={32 1},
  pages={110-5}
}
To establish whether recently described abnormalities of peak ratios are the result of changes in metabolite concentrations, quantitative 1H magnetic resonance spectroscopy was performed in 10 patients with Alzheimer disease (AD) and seven normal elderly. CSF volumes, metabolite T1 and T2 relaxation rates, ratios and concentrations of N-acetyl residues, creatine, choline residues, myo-inositol, glutamine plus glutamate (Glx), and glucose were obtained. Difference spectroscopy and quantitative… CONTINUE READING

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