Abnormal cardiac and skeletal muscle energy metabolism in patients with type 2 diabetes.

@article{ScheuermannFreestone2003AbnormalCA,
  title={Abnormal cardiac and skeletal muscle energy metabolism in patients with type 2 diabetes.},
  author={Michaela Scheuermann-Freestone and Per Lav Madsen and David Neil Manners and Andrew M. Blamire and Robin E. Buckingham and Peter Styles and George K. Radda and Stefan Neubauer and Kieran Clarke},
  journal={Circulation},
  year={2003},
  volume={107 24},
  pages={3040-6}
}
BACKGROUND It is well known that patients with type 2 diabetes have increased risk of cardiovascular disease, but it is not known whether they have underlying abnormalities in cardiac or skeletal muscle high-energy phosphate metabolism. METHODS AND RESULTS We studied 21 patients with type 2 diabetes with no evidence of coronary artery disease or impaired cardiac function, as determined by echocardiography, and 15 age-, sex-, and body mass index-matched control subjects. Cardiac high-energy… CONTINUE READING