Abnormal calcium “Sparks” in cardiomyocytes of post-myocardial infarction heart

@article{KaiHuang2008AbnormalC,
  title={Abnormal calcium “Sparks” in cardiomyocytes of post-myocardial infarction heart},
  author={恺 KaiHuang黄 and 丹 DanHuang黄 and Shengquan Fu 付生泉 and Chongzhe Yang 杨崇哲 and Yuhua Liao 廖玉华},
  journal={Journal of Huazhong University of Science and Technology [Medical Sciences]},
  year={2008},
  volume={28},
  pages={401-408}
}
In ischemic hypertrophic myocardium, contractile dysfunction can be attributed to the decreased calcium induced calcium release (CICR) in cytoplasm. This study aimed to investigate the electrophysiological properties and the expression of L calcium channel subunits in post-MI myocardium. The ischemic heart remodeling model was established in SD rats. The expressions of calcium channel subunits were determined by realtime RT-PCR. Whole cell patch clamp was used to record the electrophysiological… CONTINUE READING