Abnormal brown adipose tissue in genetically obese mice (ob/ob): effect of thyroxine.

Abstract

Lean and genetically obese (ob/ob): mice were treated daily for 2 wk with thyroxine (T4), noradrenaline, or thyroxine plus noradrenaline. T4 treatment of obese mice increased the abnormally low binding of GDP to brown adipose tissue mitochondria and permitted a cold-induced increase to occur. It also brought about a return to a more normal ultrastructure of… (More)

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Cite this paper

@article{Hogan1981AbnormalBA, title={Abnormal brown adipose tissue in genetically obese mice (ob/ob): effect of thyroxine.}, author={Sara R Hogan and Jean Himms-Hagen}, journal={The American journal of physiology}, year={1981}, volume={241 6}, pages={E436-43} }