Abnormal body perception and neural activity in the insula in depression: an fMRI study of the depressed "material me".

@article{Wiebking2010AbnormalBP,
  title={Abnormal body perception and neural activity in the insula in depression: an fMRI study of the depressed "material me".},
  author={Christine Wiebking and Andr{\'e} Bauer and Moritz de Greck and Niall W. Duncan and Claus Tempelmann and Georg Northoff},
  journal={The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry},
  year={2010},
  volume={11 3},
  pages={538-49}
}
OBJECTIVES In addition to affective-cognitive symptoms, patients with major depressive disorder (MDD) suffer from somato-vegetative symptoms, suggesting abnormal interoceptive awareness of their "material me". While recent imaging studies have extensively investigated affective-cognitive symptoms in MDD, the neural correlates of somato-vegetative symptoms and abnormal interoception remain unclear. Since the "material me" has been especially associated with the anterior insula in healthy… CONTINUE READING

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