Abnormal blood flow and red blood cell deformability in severe malaria.

@article{Dondorp2000AbnormalBF,
  title={Abnormal blood flow and red blood cell deformability in severe malaria.},
  author={Arjen Mattheus Dondorp and Piet A. Kager and Jacqueline A. C. Vreeken and Nicholas J. White},
  journal={Parasitology today},
  year={2000},
  volume={16 6},
  pages={228-32}
}
Obstruction of the microcirculation plays a central role in the pathophysiology of severe malaria. Here, Arjen Dondorp and colleagues describe the various contributors to impaired microcirculatory flow in falciparum malaria: sequestration, rosetting and recent findings regarding impaired red blood cell deformability. The correlation with clinical findings and possible therapeutic consequences are discussed.