Abnormal amygdala resting-state functional connectivity in adolescent depression.

  title={Abnormal amygdala resting-state functional connectivity in adolescent depression.},
  author={Kathryn Cullen and Melinda K Westlund and Bonnie Klimes-Dougan and Bryon A. Mueller and Alaa Houri and Lynn E. Eberly and Kelvin O. Lim},
  journal={JAMA psychiatry},
  volume={71 10},
IMPORTANCE Major depressive disorder (MDD) frequently emerges during adolescence and can lead to persistent illness, disability, and suicide. The maturational changes that take place in the brain during adolescence underscore the importance of examining neurobiological mechanisms during this time of early illness. However, neural mechanisms of depression in adolescents have been understudied. Research has implicated the amygdala in emotion processing in mood disorders, and adult depression… CONTINUE READING
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