Abnormal activity in hypothalamus and amygdala during humour processing in human narcolepsy with cataplexy.

@article{Schwartz2008AbnormalAI,
  title={Abnormal activity in hypothalamus and amygdala during humour processing in human narcolepsy with cataplexy.},
  author={Sophie Schwartz and Aur{\'e}lie Ponz and Rositsa Poryazova and Esther Werth and Peter Boesiger and Ramin Khatami and Claudio Bassetti},
  journal={Brain : a journal of neurology},
  year={2008},
  volume={131 Pt 2},
  pages={514-22}
}
Narcolepsy with cataplexy (NC) is a complex sleep-wake disorder, which was recently found to be associated with a reduction or loss of hypocretin (HCRT, also called orexin). HCRT is a hypothalamic peptide implicated in the regulation of sleep/wake, motor and feeding functions. Cataplexy refers to episodes of sudden and transient loss of muscle tone triggered by strong, mostly positive emotions, such as hearing or telling jokes. Cataplexy is thought to reflect the recruitment of ponto-medullary… CONTINUE READING
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