Abnormal accumulation of human transmembrane (TMEM)-176A and 176B proteins is associated with cancer pathology.

@article{Cuajungco2012AbnormalAO,
  title={Abnormal accumulation of human transmembrane (TMEM)-176A and 176B proteins is associated with cancer pathology.},
  author={Math P Cuajungco and William Podevin and Vinod K Valluri and Quang Bui and Van Hai Nguyen and Katrina Taylor},
  journal={Acta histochemica},
  year={2012},
  volume={114 7},
  pages={705-12}
}
Transmembrane (TMEM)-176A and 176B proteins belong to the MS4A family of proteins whose function in the immune system remains unclear. TMEM176A transcripts were previously shown to be elevated in liver cancer or kidney tissue with proteinuria, while marked changes in TMEM176B transcripts have been found in tolerated tissue allografts and neoplastic… CONTINUE READING