Abnormal Mineral Composition of Osteogenesis Imperfecta Bone as Determined by Electron Probe X-ray Microanalysis on Conventional and Cryosections

@article{Sarathchandra1999AbnormalMC,
  title={Abnormal Mineral Composition of Osteogenesis Imperfecta Bone as Determined by Electron Probe X-ray Microanalysis on Conventional and Cryosections},
  author={Padmini Sarathchandra and Mike V Kayser and Shazia Y. Ali},
  journal={Calcified Tissue International},
  year={1999},
  volume={65},
  pages={11-15}
}
Osteogenesis imperfecta (OI) is a genetic disorder of the connective tissue characterized by frequent bone fractures. The cause of bone fragility is still unknown even though substantial work on collagen has been done. We measured the calcium to phosphorus ratio (Ca/P) of bone mineral from 35 OI bone samples and 25 age- and site-matched control specimens… CONTINUE READING