Abnormal Metabolic Connectivity in Rats at the Acute Stage of Ischemic Stroke

@article{Liang2018AbnormalMC,
  title={Abnormal Metabolic Connectivity in Rats at the Acute Stage of Ischemic Stroke},
  author={Shengxiang Liang and Xiaofeng Jiang and Qingqing Zhang and Shaofeng Duan and Tianhao Zhang and Qi Huang and Xi Jun Sun and Hua Qing Liu and Jie Dong and Weilin Liu and Jing Tao and Shujun Zhao and Binbin Nie and Lidian Chen and Baoci Shan},
  journal={Neuroscience Bulletin},
  year={2018},
  volume={34},
  pages={715-724}
}
Stroke at the acute stage is a major cause of disability in adults, and is associated with dysfunction of brain networks. However, the mechanisms underlying changes in brain connectivity in stroke are far from fully elucidated. In the present study, we investigated brain metabolism and metabolic connectivity in a rat ischemic stroke model of middle cerebral artery occlusion (MCAO) at the acute stage using 18F-fluorodeoxyglucose positron emission tomography. Voxel-wise analysis showed decreased… CONTINUE READING
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