Abnormal Medial Prefrontal Cortex Resting-State Connectivity in Bipolar Disorder and Schizophrenia

@article{Chai2011AbnormalMP,
  title={Abnormal Medial Prefrontal Cortex Resting-State Connectivity in Bipolar Disorder and Schizophrenia},
  author={Xiaoqian J. Chai and Susan L. Whitfield-Gabrieli and Ann K. Shinn and John D. E. Gabrieli and Alfonso Nieto Casta{\~n}{\'o}n and Julie M. McCarthy and Bruce M Cohen and Dost {\"O}ng{\"u}r},
  journal={Neuropsychopharmacology},
  year={2011},
  volume={36},
  pages={2009-2017}
}
Bipolar disorder and schizophrenia overlap in symptoms and may share some underlying neural substrates. The medial prefrontal cortex (MPFC) may have a crucial role in the psychophysiology of both these disorders. In this study, we examined the functional connectivity between MPFC and other brain regions in bipolar disorder and schizophrenia using resting-state functional magnetic resonance imaging (fMRI). Resting-state fMRI data were collected from 14 patients with bipolar disorder, 16 patients… CONTINUE READING
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