Abnormal Mechanical Loading Induces Cartilage Degeneration by Accelerating Meniscus Hypertrophy and Mineralization After ACL Injuries In Vivo.

@article{Du2016AbnormalML,
  title={Abnormal Mechanical Loading Induces Cartilage Degeneration by Accelerating Meniscus Hypertrophy and Mineralization After ACL Injuries In Vivo.},
  author={Guoqing Du and Hongsheng Zhan and Daofang Ding and Shaowei Wang and Xiaochun Wei and Fangyuan Wei and Jianzhong Zhang and Bahar Bilgen and Anthony M. Reginato and Braden C. Fleming and Jiusheng Deng},
  journal={The American journal of sports medicine},
  year={2016},
  volume={44 3},
  pages={
          652-63
        }
}
BACKGROUND Although patients with an anterior cruciate ligament (ACL) injury have a high risk of developing posttraumatic osteoarthritis (PTOA), the role of meniscus hypertrophy and mineralization in PTOA after an ACL injury remains unknown. PURPOSE/HYPOTHESIS The purpose of this study was to determine if menisci respond to abnormal loading and if an ACL injury results in meniscus hypertrophy and calcification. The hypotheses were that (1) abnormal mechanical loading after an ACL injury… CONTINUE READING
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