Abnormal LDIflare but Normal Quantitative Sensory Testing and Dermal Nerve Fiber Density in Patients with Painful Diabetic Neuropathy

@article{Krishnan2009AbnormalLB,
  title={Abnormal LDIflare but Normal Quantitative Sensory Testing and Dermal Nerve Fiber Density in Patients with Painful Diabetic Neuropathy },
  author={Singhan T.M. Krishnan and Cristian Quattrini and Maria Jeziorska and Rayaz A. Malik and Gerry Rayman},
  journal={Diabetes Care},
  year={2009},
  volume={32},
  pages={451 - 455}
}
OBJECTIVE Abnormal small nerve fiber function may be an early feature of diabetic neuropathy and may also underlie painful symptoms. Methods for assessing small-fiber damage include quantitative sensory testing (QST) and determining intraepidermal nerve fiber density. We recently described a reproducible physiological technique, the LDIflare, which assesses small-fiber function and thus may reflect early dysfunction before structural damage. The value of this technique in painful neuropathy was… CONTINUE READING
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