Abnormal HDL apolipoprotein A-I and A-II kinetics in hemodialysis patients: a stable isotope study.

@article{Okubo2004AbnormalHA,
  title={Abnormal HDL apolipoprotein A-I and A-II kinetics in hemodialysis patients: a stable isotope study.},
  author={Keiko Okubo and Katsunori Ikewaki and Soichi Sakai and Norio Tada and Yoshihiko Kawaguchi and Seibu Mochizuki},
  journal={Journal of the American Society of Nephrology : JASN},
  year={2004},
  volume={15 4},
  pages={
          1008-15
        }
}
Low levels of HDL cholesterol and its major apoprotein constituents apoA-I and apoA-II are common in patients who have ESRD and are undergoing hemodialysis (HD), but the metabolic basis for the low HDL is poorly understood. This study aimed to investigate in vivo metabolism of apoA-I and apoA-II in five normotriglyceridemic ESRD-HD patients and compared it with five control subjects using endogenous stable isotope labeling methods coupled with a multicompartmental modeling. HDL cholesterol… CONTINUE READING
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HDL cholesterol, apolipoproteins, and cardiovascular risk in hemodialysis patients.

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