Abnormal FISH in patients with immunoglobulin light chain amyloidosis is a risk factor for cardiac involvement and for death

@inproceedings{Warsame2015AbnormalFI,
  title={Abnormal FISH in patients with immunoglobulin light chain amyloidosis is a risk factor for cardiac involvement and for death},
  author={Rahma M Warsame and S Kumar and Morie A Gertz and Martha Q. Lacy and Francis K Buadi and Suzanne R. Hayman and Nelson Leung and David Dingli and John A. Lust and Rhett P. Ketterling and Yi Lin and Stephen Russell and Lisa Hwa and Prashant Kapoor and Ronald S Go and Steven R. Zeldenrust and Robert A Kyle and S Vincent Rajkumar and Angela Dispenzieri},
  booktitle={Blood cancer journal},
  year={2015}
}
Importance of interphase fluorescent in situ hybridization (FISH) with cytoplasmic staining of immunoglobulin FISH (cIg-FISH) on bone marrow is not well understood in light chain amyloidosis (AL). This is in contrast with multiple myeloma where prognostic and treatment related decisions are dependent on cytogenetic testing. This retrospective study reviewed 401 AL patients with cIg-FISH testing performed at our institution between 2004 and 2012. Eighty-one percent of patients had an abnormal… CONTINUE READING
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