Abnormal Brain Structure Implicated in Stimulant Drug Addiction

@article{Ersche2012AbnormalBS,
  title={Abnormal Brain Structure Implicated in Stimulant Drug Addiction},
  author={Karen D. Ersche and P. Simon Jones and Guy B. Williams and Abigail J. Turton and Trevor William Robbins and Edward T. Bullmore},
  journal={Science},
  year={2012},
  volume={335},
  pages={601 - 604}
}
Nature or Drug Abuse? There are significant structural changes in striatal and prefrontal brain regions of stimulant drugdependent individuals. However, it is not clear if these brain abnormalities predate drug-taking, rendering individuals vulnerable for the development of dependence, or if these changes are the effect of many years of drug use. Ersche et al. (p. 601; see the Perpective by Volkow and Baler) investigated brain abnormalities in both drug-dependent individuals and in their… 
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