Ablation of the sphenopalatine ganglion does not attenuate the infarct reducing effect of vagus nerve stimulation.

@article{Ay2013AblationOT,
  title={Ablation of the sphenopalatine ganglion does not attenuate the infarct reducing effect of vagus nerve stimulation.},
  author={Ilknur Ay and Hakan Ay},
  journal={Autonomic neuroscience : basic & clinical},
  year={2013},
  volume={174 1-2},
  pages={31-5}
}
Electrical stimulation of the cervical vagus nerve reduces infarct size by approximately 50% after cerebral ischemia in rats. The mechanism of ischemic protection by vagus nerve stimulation (VNS) is not known. In this study, we investigated whether the infarct reducing effect of VNS was mediated by activation of the parasympathetic vasodilator fibers that originate from the sphenopalatine ganglion (SPG) and innervate the anterior cerebral circulation. We examined the effects of electrical… CONTINUE READING