Ability of small animal cells to support the postintegration phase of human immunodeficiency virus type-1 replication.

Abstract

We examine the potential for a broad range of small animal cells, including rodent, mink, and avian cells, from multiple tissues to support postintegration steps of HIV-1 replication. These cells were engineered so as to support a stable expression of human cyclin T1 and were further transduced with HIV-1 gag and pol genes. Viral gene expression was… (More)

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