Ability of Innate Defence Regulator Peptides IDR-1002, IDR-HH2 and IDR-1018 to Protect against Mycobacterium tuberculosis Infections in Animal Models

@inproceedings{RivasSantiago2013AbilityOI,
  title={Ability of Innate Defence Regulator Peptides IDR-1002, IDR-HH2 and IDR-1018 to Protect against Mycobacterium tuberculosis Infections in Animal Models},
  author={Bruno Rivas-Santiago and J E Casta{\~n}eda-Delgado and Cesar E. Rivas Santiago and Matt Waldbrook and Irma Gonz{\'a}lez-Curiel and Juan C. Le{\'o}n–Contreras and Jos{\'e} Antonio Enciso-Moreno and Victor del Villar and Jazmin Mendez-Ramos and Robert E. W. Hancock and Rogelio E Hern{\'a}ndez-Pando},
  booktitle={PloS one},
  year={2013}
}
Tuberculosis is an ongoing threat to global health, especially with the emergence of multi drug-resistant (MDR) and extremely drug-resistant strains that are motivating the search for new treatment strategies. One potential strategy is immunotherapy using Innate Defence Regulator (IDR) peptides that selectively modulate innate immunity, enhancing chemokine induction and cell recruitment while suppressing potentially harmful inflammatory responses. IDR peptides possess only modest antimicrobial… CONTINUE READING
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