Ability To Serologically Confirm Recent Zika Virus Infection in Areas with Varying Past Incidence of Dengue Virus Infection in the United States and U.S. Territories in 2016.

@article{Lindsey2017AbilityTS,
  title={Ability To Serologically Confirm Recent Zika Virus Infection in Areas with Varying Past Incidence of Dengue Virus Infection in the United States and U.S. Territories in 2016.},
  author={Nicole P Lindsey and J. Erin Staples and Krista M Powell and Ingrid B. Rabe and Marc Fischer and Ann M Powers and Olga I. Kosoy and Eric C. Mossel and Jorge Luis Mu{\~n}oz-Jord{\'a}n and Manuela Beltr{\'a}n and W. Thane Hancock and Karrie-Ann E. Toews and Esther M. Ellis and Brett R. Ellis and Amanda J. Panella and Alison Jane Basile and Amanda E Calvert and Janeen J. Laven and Christin H. Goodman and Carolyn V. Gould and Stacey W. Martin and Jennifer Dolan Thomas and Julie Villanueva and Mary L Mataia and Rebecca H Sciulli and Remedios B Gose and A. Christian Whelen and Susan L Hills},
  journal={Journal of clinical microbiology},
  year={2017},
  volume={56 1}
}
Cross-reactivity within flavivirus antibody assays, produced by shared epitopes in the envelope proteins, can complicate the serological diagnosis of Zika virus (ZIKAV) infection. We assessed the utility of the plaque reduction neutralization test (PRNT) to confirm recent ZIKAV infections and rule out misleading positive immunoglobulin M (IgM) results in areas with various levels of past dengue virus (DENV) infection incidence. We reviewed PRNT results of sera collected for diagnosis of ZIKAV… CONTINUE READING
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