Aberrant septin 9 DNA methylation in colorectal cancer is restricted to a single CpG island

@inproceedings{Wasserkort2013AberrantS9,
  title={Aberrant septin 9 DNA methylation in colorectal cancer is restricted to a single CpG island},
  author={Reinhold Wasserkort and Alexandra Kalm{\'a}r and G{\'a}bor Valcz and S{\'a}ndor Spis{\'a}k and Manuel Krispin and Kinga T{\'o}th and Zsolt Tulassay and Andrew Z. Sledziewski and B{\'e}la Moln{\'a}r},
  booktitle={BMC Cancer},
  year={2013}
}
The septin 9 gene (SEPT9) codes for a GTP-binding protein associated with filamentous structures and cytoskeleton formation. SEPT9 plays a role in multiple cancers as either an oncogene or a tumor suppressor gene. Regulation of SEPT9 expression is complex and not well understood; however, hypermethylation of the gene was recently introduced as a biomarker for early detection of colorectal cancer (CRC) and has been linked to cancer of the breast and of the head and neck. Because the DNA… CONTINUE READING
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