Aberrant protein expression in the placenta of cloned mouse derived from embryonic stem cell.

@article{Kim2010AberrantPE,
  title={Aberrant protein expression in the placenta of cloned mouse derived from embryonic stem cell.},
  author={Hong-Rye Kim and R. Han and T. Wakayama and Chang-Sik Park and D. Jin},
  journal={Placenta},
  year={2010},
  volume={31 10},
  pages={
          853-9
        }
}
Placentomegaly is a common phenotype in cloned mice. To assess differences in protein expression between placentae of cloned and uncloned mice, we used a proteomic approach involving 2-dimensional electrophoresis (DE) and MALDI-TOF MS. Proteins within isoelectric point range of 4-11 separately were analyzed in 2-DE with 3 replications of each sample. A total of approximately 3500 spots were detected in placental 2-DE stained with Coomassie blue. In the comparison of normal and cloned samples, a… Expand
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