Aberrant placenta gene expression pattern in bovine pregnancies established after transfer of cloned or in vitro produced embryos.

@article{SalilewWondim2013AberrantPG,
  title={Aberrant placenta gene expression pattern in bovine pregnancies established after transfer of cloned or in vitro produced embryos.},
  author={Dessie Salilew-Wondim and Dawit Jember Tesfaye and Munir Hossain and Eva Held and Franca Rings and Ernst Tholen and Christian Looft and Ulas Cinar and Karl Schellander and M. Hoelker},
  journal={Physiological genomics},
  year={2013},
  volume={45 1},
  pages={
          28-46
        }
}
In the present study, we used the global transcriptome profile approach to identify dysregulated genes, molecular pathways, and molecular functional alterations in bovine placentas derived from somatic cell nuclear transfer (SCNT) and in vitro embryo production (IVP) pregnancies compared with their artificial insemination (AI) counterparts at day 50 of gestation. For this, day 7 blastocysts derived from AI, IVP, or SCNT were transferred to oestrus-synchronized cows. The pregnant animals were… 
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Global DNA methylation: role, status and genome-wide approaches to study epigenetic mark in cloned embryos
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The overall status of globalDNA methylation, the effect of aberrant DNA methylation on development and evolution in methodologies used for profiling global DNA methylome in cloned embryos is compiled.
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