Aberrant kinetics of bone marrow-derived endothelial progenitor cells in the murine oxygen-induced retinopathy model.

@article{Nakagawa2011AberrantKO,
  title={Aberrant kinetics of bone marrow-derived endothelial progenitor cells in the murine oxygen-induced retinopathy model.},
  author={Yoshihiro Nakagawa and Haruchika Masuda and Rie Ito and Michiru Kobori and Mika Wada and Tomoko Shizuno and Atsuko Sato and Takahiro Suzuki and Kenji Kawai and Takayuki Asahara},
  journal={Investigative ophthalmology & visual science},
  year={2011},
  volume={52 11},
  pages={
          7835-41
        }
}
PURPOSE Retinopathy of prematurity (ROP) causes serious blindness because of the vasculopathy that results from the abnormal oxygen dynamics. However, the systemic kinetics of bone marrow-derived endothelial progenitor cells (BM-derived EPCs) during the "postnatal vasculogenesis " of ROP has yet to be elucidated. Thus, the authors investigated the kinetics of BM-derived EPCs using a murine oxygen-induced retinopathy (OIR) model. METHODS OIR was induced in C57BL/6J mice by continual aeration… CONTINUE READING